Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 10. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_2769Respiratory synctial viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman skin cancer cell lineA43115E+3 cells per wellNAMTT assay1 MOIModerate cell death after 24 hoursNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23487261
OV_2770Respiratory synctial viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman skin cancer cell lineA43115E+3 cells per wellNAMTT assay1 MOIModerate cell death after 36 hoursNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23487261
OV_2771Respiratory synctial viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman skin cancer cell lineA43115E+3 cells per wellNAMTT assay1 MOIMaximum cell death after 48 hoursNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23487261
OV_2772Respiratory synctial viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman skin cancer cell lineA43115E+3 cells per wellNAMTT assay3 MOIModerate cell death after 24 hoursNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23487261
OV_2773Respiratory synctial viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman skin cancer cell lineA43115E+3 cells per wellNAMTT assay3 MOISignificant cell death after 36 hoursNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23487261
OV_2774Respiratory synctial viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman skin cancer cell lineA43115E+3 cells per wellNAMTT assay3 MOIMaximum cell death after 48 hoursNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23487261
OV_5887Respiratory synctial virusMutantRNAParamyxoviridaeNoneYesNoNoATCCHuman RWPE-1 cell lineHuman RWPE-1 cell lineNANAMTT assay2 MOISlight reduction in tumor growthNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANAUS9241998
OV_5888Respiratory synctial virusMutantRNAParamyxoviridaeNoneYesNoNoATCCHuman prostate cancer cell linePC-3NANAMTT assay2 MOI20% cell survived after treatmentNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANAUS9241998
OV_5889Respiratory synctial virusMutantRNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic nude mice xenograft for PC-3 (3.0E+6), below ear1.0E+6 pfuNA Tumor volume reduced to 200mm after 38 days compared to control 1200mmIntratumoralInduction of apoptosis as measured by TUNEL assayNANAUS9241998
OV_5890Respiratory synctial virusMutantRNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic nude mice xenograft for PC-3 (3.0E+6), below ear1.0E+6 pfuNA Tumor volume reduced to 300mm after 35 days compared to control 900mmIntratumoralInduction of apoptosis as measured by TUNEL assayNANAUS9241998